Torcetrapib for increasing HDL cholesterol
April 9, 2004 by admin · Leave a Comment
On April 7, 2004 Pfizer announced preliminary results of a Phase I trial with torcetrapib, its experimental therapy for increasing HDL cholesterol. A study was published in the April 8, 2004 issue of the New England Journal of Medicine, involving 19 patients. The results showed that torcetrapib significantly increased the level of high-density lipoprotein (HDL) [...]
Enoximone
March 26, 2004 by admin · Leave a Comment
On March 25, 2004 Myogen Inc. announced preliminary results from its Phase III clinical trial of enoximone capsules. The 201 participants were patients with the most advanced stages of chronic heart failure who were dependent on intravenous (IV) inotrope therapy. The study was designed to evaluate enoximone capsules as an effective treatment to wean patients [...]
Taxus Express
March 5, 2004 by admin · Leave a Comment
On March 4, 2004, Boston Scientific announced that Taxus Express, its paclitaxel-eluting stent system for the treatment of coronary artery disease, had received FDA approval. The company indicated that it planned to launch Taxus Express in the United States immediately. Cordis Corporation’s Cypher™ stent (see Week and the newly approved Taxus stent are currently the [...]
CYPHER Sirolimus-eluting Stent
February 20, 2004 by admin · Leave a Comment
On February 18, 2004, Cordis Corporation announced completion of patient enrollment in the first randomized head-to-head coronary stent trial comparing its new CYPHER sirolimus-eluting coronary stent with the Taxus Express (2) paclitaxel-eluting coronary stent. This trial is expressly designed to compare performance differences between the two drug-eluting stents, particularly in high-risk patient group subsets such [...]